Ivermectin is one of the few antiparasitic drugs available for human use. It was invented and manufactured in the 20th century and has contributed to the elimination of parasitic infections to people in many African countries where this was the first reason for death in both adulthood and childhood.
In this article we are going to analyze the benefits and drawbacks of Ivermectin and be sure to offer the best possible answers to the pressing questions for this active substance. Its use is wide not only for internists but also for dermatologists who want Ivermectin for Rosacea a type of acne that has to do with Demodex one of the most persistent parasites that live on human skin.
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What Is Ivermectin and How Does It Work?
Ivermectin is a drug that belongs to the class of macrocyclic lactones or anthelmintics. These drugs are specifically created to kill parasites by interfering to basic metabolic paths within their cells. As the first line of action, we have Ivermectin that interferes with parasite’s nervous system and muscular mass. It blocks the glutamate-gated chloride channels and blocks the neurotransmission in the parasites’ cells. That paralysis is the main reason parasites remain without energy and cannot digest anything as a result they die.
How does Ivermectin work?
As mentioned earlier Ivermectin is a powerful drug that acts directly within the parasites’ cells. It can deactivate the glutamate-chloride paths receptors within the cells. That action can cause a cease in the neurotransmission within the parasite’s cell and then the energy and metabolism stops. It is enough for parasites to stop digesting food and come to the phase of apoptosis that is the closest thing to death. Ivermectin is one of the high-class drugs in this category offering tremendous results as being one of the most effective and cost for benefit substances.
Where to Get Ivermectin for Humans
Even though Ivermectin is one of the most highly prescribed drugs, you may not need a prescription for it. It is easy to have Ivermectin online by logging in to
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Understanding Ivermectin Dosage for Humans
It is good to know that Ivermectin is a safe drug only when taken under the authority and orders of a trained medical professional. Self-medicating for Ivermectin can be really dangerous especially when you reach the higher dosage limit that crosses the line with toxicity for this drug. The requested safe dosage for humans who need to take Ivermectin would be 200 micrograms (mcg) per kilogram of body weight.
It depends on the parasitic infection type you need to eliminate thus the use of Ivermectin could be from as low as 150 mcg daily or step up to 200 mcg daily that is the highest safe dose a human being could have.
How to Take Ivermectin Safely
Getting a prescription from a qualified physician is the first step to take Ivermectin safely. Most of the times a single oral dose is enough for Ivermectin to treat all conditions having to do with parasitic infections. However, if you are immunocompromised you may need to take a second dose of Ivermectin within the day, but this is something that only your doctor can decide.
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Potential Side Effects of Ivermectin
Like any other drug, Ivermectin may cause some potential side effects to your body. However, these side effects severity and gravity vary according to factors such as the overall health of the individual, the dosage scheme and the particular parasitic infection that is about to be treated.
There is a high correlation of side effects with Ivermectin when you exceed the regular dose scheme and when you take this drug without a direct medical staff supervision. Here is a shortlist of the potential side effects that you can have with Ivermectin:
- Reactions from the skin: Allergies and rashes could happen
- Neurological: Weakness, tiredness, dizziness and lightheadedness are some of the neurological side effects of Ivermectin one may experience
- Issues with the gut: You can feel nauseous, experience vomiting or diarrhea and abdominal pain when taking Ivermectin the wrong way
- Muscle skeletal pain
- Mazzotti reaction: It is when parasites die in large volumes and numbers after the Ivermectin action and can cause fever and headache to people. It is more common when Ivermectin is used to treat larval worms infection to humans
- Eye problems
- Liver problems
- Lower blood pressure
All these side effects are temporary and can be easily reversed by adjusting the dosage of Ivermectin.
Ivermectin is an FDA Approved Medication
Ivermectin is an FDA-approved medication for the following conditions:
- Intestinal strongyloidiasis
- Onchocerciasis
- Topical formulation of Ivermectin for Rosacea and head lice
All other uses of Ivermectin are off-label including the potential use against COVID-19 infection.
Dosage and Administration
Ivermectin administration is most of the times oral and it comes in pills of 200 mcg per tablet concentration. It is good to take ivermectin with an empty stomach and use only one glass of water to swallow the tablet. You must take Ivermectin one or two hours after a meal as the drastic substance of the drug could interact with stomach content and lose its potency.
Warnings of Ivermectin
There are some warnings that come with the intake of Ivermectin:
- Potential Risk of Severe Neurological Side Effects (encephalopathy with the Loa Loa African worm infection, seizures and coma.
- Mazzotti Reaction: It usually comes as a response to Ivermectin taken in big doses, against the Onchocerciasis disease, that can cause fever, joint paint, rashes, headache and swollen lymph nodes to patients.
- Interactions with other drugs: Patients taking Ivermectin should limit the intake of blood thinners (warfarin) or HIV-infection drugs.
- Liver function possible impairment: As Ivermectin is metabolized in the liver, it is not impossible to affect it in a negative way.
Benefits of Ivermectin
Ivermectin can offer great benefits to patients suffering from parasitic infections. Here is a list of the potential benefits:
- Controls Disease Progression
- Ivermectin is ideal for Mass population administration and elimination of pandemics in worm infections
- It Can help by braking the transmission cycle to humans who are infected with parasites
- High efficiency in human intestinal strongyloidiasis a severe parasitic infection of the gut.
- Effective treatment for Rosacea and Head Lice
- It offers a great safety profile when the dosage scheme is close to the FDA-approved one.
Is It Legal to Buy Ivermectin for Humans Online?
Yes, it is legal to buy Ivermectin for humans online. However, you are strongly recommended to have a doctor’s prescription before you buy Ivermectin so that you know exactly the dosage you need to follow and be safe.
FAQ's
This has to do with your treating physician and the type of parasitic infection you suffer from. Generally, it is safe to take Ivermectin 12mg daily for several days and make sure you have no side effects coming out of this practice.
There is a chance to buy Ivermectin 12mg online in stores like ivermectinseller.com, which is one of the biggest and most reliable online drug retailers that deliver to your home with expedited shipping.
The peak plasma concentration for Ivermectin 12mg is 4 to 10 hours after the initial administration. The half-life of this drug is typically close to 18 hours so you need more than 36 hours to completely remove Ivermectin from your body. Within the window of 4 to 10 hours after administration. Ivermectin is very active and effective to treat parasitic conditions anywhere in your body.
Ivermectin is an extremely safe drug for humans provided you use it with care and respect the dosage scheme according to the specific parasitic infection you suffer from. All side effects of Ivermectin have to do with overdose and that is why you need to be extra careful when taking this medicine.
Even though Ivermectin is the very same substance in both human and animal organisms, however it is quite different when getting to dosages and administration routes. While humans typically need lower doses, animals like horses will need higher doses.
On the other hand, oral and cutaneous is the only administration routes for humans. For animals, you can also have intravenous or intramuscular administration of Ivermectin and the doses are generally higher since they are infected with many more parasites.
Finally, Ivermectin for human use is controlled and monitored by FDA. On the other hand, animal Ivermectin has more indications in animals and is regulated by the FDA center for Veterinary Medicine. It is not recommended to take Ivermectin products intended for animal use, you should always opt for human-grade Ivermectin.
